学术2015033HDLCP比值

文章来源:脑动脉硬化   发布时间:2017-1-3 0:32:39   点击数:
  

(英文原文)Cholesterol-OverloadedHDLParticlesAreIndependentlyAssociatedWithProgressionofCarotidAtherosclerosisinaCardiovascularDisease-FreePopulation

BackgroundCholesterol-overloadedhigh-densitylipoprotein(HDL)particlesexertanegativeimpactontheantiatherogenicfunctionofHDLinexperimentalstudies.However,itremainsunclearwhethercholesterol-overloadedHDLparticleisinvolvedinthedevelopmentofatherosclerosisinhumans.

ObjectivesTheobjectiveofthisstudywastoexplorewhethercholesterol-overloadedHDLparticlesareassociatedwiththeprogressionofcarotidatherosclerosisinacardiovasculardisease–freepopulation.

MethodsBaselineHDLparticlenumberwasmeasuredusingnuclearmagneticresonancespectroscopyinparticipantsages45to74yearsina







































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